lecture slides Powerpoint Slides Week1 1 4 Effective Solute & Water Transport revised
EFFECTIVE SOLUTES & WATER TRANSPORT LEARNING OBJECTIVES " Explain osmosis " Contrast osmolarity and tonicity " Explain how effective solutes regulate fluid compartments of the body. GENERAL CONCEPTS 1. The two fluid compartments of the body, intracellular fluid (ICF) and extracellular fluid (ECF), are in osmotic balance. 2. Water moves by facilitated diffusion through aquaporin channels across most cell membranes. This process is called osmosis. 3. Non-permeable solutes are called effective solutes. Cellular volume is critically dependent on the steady state of effective solutes and water across the cell membrane in exchange with the extracellular fluid compartment (ECF). 4. Cells shrink in hypertonic ECF conditions. Cells swell in Hypotonic ECF conditions.