F00574 011 f003

An overgrowth of normal/near-normal cells without invasion would be benign (e.g. fibroadenoma of the breastj

Malignant cells that have not invaded or metastasised—often called pre-invasive or carcinoma in situ (e.g. DCIS in breast, CIN I-III of cervix)

Malignant cells that have locally invaded. e.g. through the basement membranę—invasive carcinoma

Malignant cells in another tissue (liver, lung. bonę marrow) —metastatic cancer

© Elsevier. Boon et al.: Davidson's Principles and Practice of Mediclne 20e - www.studentconsult.com

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