IMG 88 (3)
Functions of secretory immunoglobulins
1. Immune 6xclusion
/ Secreted IgA binds to microbes and prevents them from attaching to or penetrating the epithelial lining
/ Demonstrated for bacteria and viruses
2. Neutralization
/ Secreted IgA binds to microbial toxins at sites, which either inactivate the toxin’s^ enzymatic properties or inhibit the toxin’s ability to attach to target cells
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