netter170
Thyroid Gland: Hormone Action
ENDOCRINE PHYSIOLOCY
T4®
t co3
f Ventilation
f Cardiac output
Whole Body Effects
f Renal function
J. Perkins
MS, MFA
Figurę 8.10 Thyroid Hormone Action
Thyroxine (TĄ) is converted to triiodothyronme (T,) al target Iłssues. T, binds to a nuclear receptor, resulting in transcription of a host of cellular proteins and enzymes. The net effect is an increase in meta-bolic ratę and 0;. consumption. These effects are associated with increased heart, lung, and kidney function. T, is also important for norma! growth and development.
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