57225 netter117
Potassium Excretion
RENAL PHYSIOLOGY
Low K’ Diet Normal and High K* Diet
|
Physiologic Factors That Stimulate K* Secretion |
Physiologic Factors That Stimulate K* Reabsorption |
Factors That Alter K* Secretion (Stimulate) |
Factors That Alter Kł Secretion (Inhibit) |
|
Aldosteronc Hyperkalemia |
Low K* diet |
Increased urine llow ratę Acute and chronic alkalosis Chronić acidosis |
Acute acidosis _ |
J. Perkins
MS, MF.A «!BVI
Figurę 6.15 Potassium Excretion_
The kidneys are the primary route for excretion of K ’ trom Ilu* body, and the amount excreted vari«*s wilh dietary K' intake. On a low K* diet, only about 1% of the filtered load is excreted. With a normal or high K’ diet, varying amounts of K' are excrcted. Most of the K- that is excreted under these conditions reflects K* that is secreted into the tubular fluid by the collecting duet. The principal celi of the col-lecting duet secretes K*, while the intercalated celi of the collectinę duet is thought to be involved in K' rcabsorption during a low k' diet. The mechanisms of K reabsorption by the proximal tubule thick ascending limb of Henle's loop are depicted in Figurę G.8. a' these are not influenced by dietary K*.
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