IMGP5555

IMGP5555



Neurofibromatosis type 1

• Clinicai Diagnosis

•    Si.v or morę cafć au lait maculcs ovcr 5 mm in grcatcst diameterin prepubertal individuals and over 15 mm in greatcst dianie ter in postpubcrtal individuals

•    Two or morę neurofibromas of any type or one plexifbrm neurofibrnma

•    Frcckling in the axillary or inguinal regions

•    Optic glioma

•    Two or mnrc Lisch nodules (iris hamartomas)

A distinctitc osscous lesion such as sphenoid dysplasia or thinning of long bonę cortcx with or without pscudarthrnsis A flrsl-dcgrcc rclativc (pa rent, sib, or ofTspring) with NF1 as defined by the ahovc critcria


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